HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetone →
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetone | HCID 180 | — |
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | 3'-(3-Pyridylcarbonyl)-5'-pivaloyltrifluorothymidine | HCID 131716753 | — |
Reaction Steps
To 440 mg of the product of Example 105 dissolved in 10 mL of acetone, 1.0 g of methyl iodide was added. The mixture was refluxed for 10 hours, then the precipitate which formed was collected by suction filtration to give 550 mg of the desired product as yellow leaves melting at 188°-190° C. with decomposition. NMR analysis confirmed that the product had the structural formula: ##STR134##
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05024998 |
| Source dataset | uspto-grants-1991_06 |
| ORD ID | ord-8b4743bfdd88427198b3d32a9a9f10cd |
| Source note | uspto-grants-1991_06 |