Hydrochloric Acid → HCID 11074035, compound

HRID 1494332Notes

Reaction equation

HRID 1494332 reaction equation
[CH3:1][NH:2][C:3]1[CH:8]=[C:7]([O:9][CH3:10])[C:6]([O:11][CH3:12])=[CH:5][C:4]=1[N+:13]([O-])=O.Cl>C(O)C.[Pd]>[NH2:13][C:4]1[CH:5]=[C:6]([O:11][CH3:12])[C:7]([O:9][CH3:10])=[CH:8][C:3]=1[NH:2][CH3:1]

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 11020199HCID 11020199, compound

Product 1

HCID 11074035HCID 11074035, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

A solution of 0.5 g (2.4 mmol) N-methyl-4,5-dimethoxy-2-nitroanilin in 150 ml ethanol was added 1 ml 4N hydrochloric acid, and the mixture was hydrogenated at atm. pressure by using 5% Pd-C (0.1 g) as a catalyst. The reaction mixture was filtered and evaporated in vacuo to give 2-amino-4.5-dimethoxy-N-methylaniline.

Workup

  1. filtrationThe reaction mixture was filtered
  2. customevaporated in vacuo

Sources & evidence

ORD record
ord-f4a1d691509b4ee19af2223087987ddc
Source dataset
uspto-grants-1991_06
Patent number
US05026704

Reaction notes

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