o-Chlorophenylacetic acid → Acetyl chloride, 2-(2-chlorophenyl)-

HRID 1494383Notes

Reaction equation

HRID 1494383 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=O.S(Cl)([Cl:14])=O>>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([Cl:14])=[O:11]

Participants

3

Reactant 2

HCID 17124o-Chlorophenylacetic acidHCID 24386Thionyl Chloride

Product 1

HCID 182669Acetyl chloride, 2-(2-chlorophenyl)-Yield 99%

Procedure

A mixture of 30.0 g (0.176 mol) of o-chlorophenylacetic acid and 40 ml of thionyl chloride was stirred for 18 hours. The volatiles then were removed in vacuo to give 32.76 g (99.0%) of o-chlorophenylacetyl chloride as a transparent, pale yellow, mobile liquid.

Workup

  1. customThe volatiles then were removed in vacuo

Sources & evidence

ORD record
ord-e4a7a57297514dbc8b2cf4d395ffda55
Source dataset
uspto-grants-1991_06
Patent number
US05026707

Reaction notes

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