HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 1-Methyl-2-piperazinyl-8-chloro-1,2,3,4-tetrahydronaphthalene dihydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Piperazine | HCID 4837 | — |
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | 1-Methyl-8-chloro-2-tetralone | HCID 15137222 | — |
| Product | 1-Methyl-2-piperazinyl-8-chloro-1,2,3,4-tetrahydronaphthalene dihydrochloride | HCID 67829662 | — |
Reaction Steps
Using the method of Example 11, 1.94 g (10 mmol) of 1-methyl-8-chloro-2-tetralone were treated with piperazine followed by reduction with sodium borohydride and treatment with HCl to produce 0.67 g of the title compound as colorless crystals; m.p. >200° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05026707 |
| Source dataset | uspto-grants-1991_06 |
| ORD ID | ord-a98451ae542c42ca9dde70add5a22502 |
| Source note | uspto-grants-1991_06 |