Methylamine → HCID 19828083, compound

HRID 1494429Notes

Reaction equation

HRID 1494429 reaction equation
[Cl:1]C[C:3]1[N:4]=[CH:5][N:6]([S:11]([N:14]([CH3:16])[CH3:15])(=[O:13])=[O:12])[C:7]=1[CH2:8][CH2:9][CH3:10].[CH3:17][NH2:18]>>[ClH:1].[CH3:17][NH:18][C:3]1[N:4]=[CH:5][N:6]([S:11]([N:14]([CH3:15])[CH3:16])(=[O:12])=[O:13])[C:7]=1[CH2:8][CH2:9][CH3:10]

Participants

3

Reactant 2

HCID 6329MethylamineHCID 15616313HCID 15616313, compound

Product 1

HCID 19828083HCID 19828083, compound

Procedure

4-(Chloromethyl)-N,N-dimethyl-5-propyl-1H-imidazole-1-sulphonamide (189 mg) was stirred with excess methylamine (33% solution in ethanol; 5 ml) at room temperature under nitrogen for 18 h. The reaction mixture was evaporated under reduced pressure to give the title compound as an oil (167 mg), t.l.c. (System A, 100:10:1) Rf 0.21.

Workup

  1. customThe reaction mixture was evaporated under reduced pressure

Sources & evidence

ORD record
ord-9bf21ae1e4af4744a39d9e3ca840d2bd
Source dataset
uspto-grants-1991_06
Patent number
US05026722

Reaction notes

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