Propylene Oxide → HCID 15144525, compound

HRID 1494581Notes

Reaction equation

HRID 1494581 reaction equation
[SH:1][C:2]1[S:3][C:4]([SH:7])=[N:5][N:6]=1.[CH2:8]1[O:11][CH:9]1[CH3:10]>C(O)(C)C>[OH:11][CH:9]([CH3:8])[CH2:10][S:1][C:2]1[S:3][C:4]([S:7][CH2:8][CH:9]([OH:11])[CH3:10])=[N:5][N:6]=1

Participants

4

Reactant 2

HCID 6378Propylene OxideHCID 178418558HCID 178418558, compound

Product 1

HCID 15144525HCID 15144525, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

2,5-Dimercapto-1,3,4-thiadiazole(276.21 grams, 1.84 moles) and isopropanol (400 ml) were charged into a reaction flask. Propylene oxide(222.8 grams, 3.84 moles) was added at a rate sufficient to maintain reflux condition. The mixture was refluxed for 15 minutes. The solvent was stripped off by using a rotary evaporator at approximately 20 mm Hg and 100° C. The product is characterized by infrared absorption bands at 3350, 2900, 1680, 1450, 1380, 1250, 1120, 1040, 930, 740, and 705 cm-1.

Workup

  1. temperatureto maintain
  2. temperaturereflux condition
  3. temperatureThe mixture was refluxed for 15 minutes
  4. customa rotary evaporator at approximately 20 mm Hg and 100° C
  5. customThe product is characterized by infrared absorption bands at 3350, 2900, 1680, 1450, 1380, 1250, 1120, 1040, 930, 740, and 705 cm-1

Sources & evidence

ORD record
ord-7f884f3425d249c3b577941f7cd51c8f
Source dataset
uspto-grants-1991_06
Patent number
US05026865

Reaction notes

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