2,4-Diamino-6-[2-(4-carboxyphenyl)prop-1-enyl]pyrido[2,3-d]pyrimidine → HCID 178508854, compound

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Reaction Steps

In a similar fashion, 2,4-diamino-6-[2-(4-carboxyphenyl)prop-1-enyl]pyrido[2,3-d]pyrimidine is converted to 2-amino-4-hydroxy-6-[2-(4-carboxyphenyl)prop-1-enyl]pyrido[2,3-d]pyrimidine, mp>250° C.; NMR (DMSO-d6, 80 MHz) d 2.28 and 2.30(brs, 3H), 6.77 and 7.06(brs, 1H), 7.72(d, 2H, J=8.5 Hz), 7.97(d, 2H, J=8.5 Hz), 8.27(d, 1H, J=2.0 Hz), 8.72(d, 1H, J=2.0 Hz).

Provenance & Evidence