Hydrochloric Acid → HCID 14722550, compound

HRID 1494637Notes

Reaction equation

HRID 1494637 reaction equation
[Br:1][CH2:2][CH2:3][CH2:4][CH2:5][C:6]([C:15]1[CH:20]=[CH:19][C:18]([F:21])=[CH:17][CH:16]=1)([C:8]1[CH:13]=[CH:12][C:11]([F:14])=[CH:10][CH:9]=1)O.Cl>>[Br:1][CH2:2][CH2:3][CH2:4][CH:5]=[C:6]([C:8]1[CH:9]=[CH:10][C:11]([F:14])=[CH:12][CH:13]=1)[C:15]1[CH:20]=[CH:19][C:18]([F:21])=[CH:17][CH:16]=1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 14722555alpha-(4-Bromobutyl)-4-fluoro-alpha-(4-fluorophenyl)benzenemethanol

Product 1

HCID 14722550HCID 14722550, compound

Procedure

A mixture of 100 parts of α-(4-bromobutyl)-4-fluoro-α-(4-fluorophenyl)benzenemethanol and 714 parts of concentrated hydrochloric acid was stirred and refluxed for 5 hours. The reaction mixture was cooled and the product was extracted with 2,2'-oxybispropane. The extract was dried, filtered and evaporated, yielding 92 parts of 1,1'-(5-bromo-1-penten-1-ylidene)bis[4-fluorobenzene] as a residue (int. 50).

Workup

  1. temperaturerefluxed for 5 hours
  2. temperatureThe reaction mixture was cooled
  3. extractionthe product was extracted with 2,2'-oxybispropane
  4. customThe extract was dried
  5. filtrationfiltered
  6. customevaporated

Sources & evidence

ORD record
ord-bba039390bcd4b78b32290f79cecf5b0
Source dataset
uspto-grants-1991_06
Patent number
US05026853

Reaction notes

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