2-Amino-1-(2-mercapto-2-methylpropylamino)benzene → HCID 9974411, compound

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Reaction Steps

2-Amino-1-(2-mercapto-2-methylpropylamino)benzene (0.43 g, 2.19×10-3 mol) and 0.82 g (5.19×10-3 mol, 237 M %) 2-cyclopropylmethylthio-2-methylpropanal were reacted by the method of Example 2 to yield 0.63 g (85%) of 1-(2-cyclopropylmethylthio-2-methylpropylamino)-2-(2-mercapto-2-methylpropylamino)benzene as an oily product after purification by filtration through flash silica in a 350 ml sintered glass funnel, eluting with 200 ml portions of 2×100% hexane, 3×90% hexane/ether, 2×80% hexane/ether.

Provenance & Evidence