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HRID14969

反应详情

EQUATION

反应方程式

HRID 14969 的结构方程式

REACTANTS

反应物

2
结构：Clc1ccnc(Cl)n1
HCID77531

2,4-Dichloropyrimidine

C4H2Cl2N2

结构：C[C@H]1CN(C(=O)OC(C)(C)C)CCN1S(=O)(=O)c1cccc(B2OC(C)(C)C(C)(C)O2)c1
HCID67045047

未命名化合物

PRODUCTS

生成物

1
结构：C[C@H]1CN(C(=O)OC(C)(C)C)CCN1S(=O)(=O)c1cccc(-c2ccnc(Cl)n2)c1
HCID86603331

未命名化合物

收率 90%

PROCEDURE

实验过程

2,4-dichloropyrimidine and (S)-tert-butyl 3-methyl-4-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenylsulfonyl)piperazine-1-carboxylate was coupled following procedure A. The yield was 90%. LC-MS showed the product was >95% pure and had the expected M+H+ of 453.