Potassium Carbonate → 1-(4-(3-Methoxy-4-nitrophenyl)piperazin-1-yl)ethanone

Participants

Reaction Steps

The compound obtained in Step 1 above (300 mg), N-acetylpiperazine (300 mg), and potassium carbonate (500 mg) were dissolved in dimethylformamide (3 mL) and reacted at 80° C. overnight. The dimethylformamide of the reaction mixture was removed under reduced pressure, and added with water to form a solid. The solid was filtered to obtain a target compound as a yellow solid.

Provenance & Evidence