Oxalyl chloride → HCID 21445900, compound

HRID 1497006Notes

Reaction equation

HRID 1497006 reaction equation
[C:1]([OH:14])(=O)/[CH:2]=[CH:3]/[CH:4]=[CH:5]/[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].C(Cl)(=O)C([Cl:18])=O>ClCCl>[C:1]([Cl:18])(=[O:14])/[CH:2]=[CH:3]/[CH:4]=[CH:5]/[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12]

Participants

4

Reactant 2

HCID 65578Oxalyl chlorideHCID 5312382HCID 5312382, compound

Product 1

HCID 21445900HCID 21445900, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

(2E,4E)-dodeca-2,4-dienoic acid (2.5 g) was dissolved in dichloromethane (25 ml). Oxalyl chloride (2.23 ml) was added and the reaction mixture was stirred at room temperature for 3 h. Solvent and excess oxalyl chloride were removed, and the residue was stripped several times with DCM. The crude acid chloride was used as such in next step.

Workup

  1. customSolvent and excess oxalyl chloride were removed

Sources & evidence

ORD record
ord-5f1e17c4ff6b44fb89e3e07d9b98a8c1
Source dataset
uspto-grants-2015_12
Patent number
US09199948B2

Reaction notes

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