Phosphorus oxychloride → HCID 86682943, compound

HRID 1497076Notes

Reaction equation

HRID 1497076 reaction equation
[CH3:1][O:2][C:3]([C:5]1[C:6](=O)[NH:7][C:8]2[C:13]([C:14]=1[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)=[CH:12][C:11]([Cl:21])=[CH:10][C:9]=2[Cl:22])=[O:4].O=P(Cl)(Cl)[Cl:26]>>[CH3:1][O:2][C:3]([C:5]1[C:6]([Cl:26])=[N:7][C:8]2[C:13]([C:14]=1[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)=[CH:12][C:11]([Cl:21])=[CH:10][C:9]=2[Cl:22])=[O:4]

Participants

3

Reactant 2

HCID 24813Phosphorus oxychlorideHCID 86682942HCID 86682942, compound

Product 1

HCID 86682943HCID 86682943, compound

Procedure

The title compound was prepared in analogy to example 11 step B from 6,8-dichloro-2-oxo-4-phenyl-1,2-dihydro-quinoline-3-carboxylic acid methyl ester and POCl3. Light brown solid. MS (ESI): 366.0 (M+H)+.

Sources & evidence

ORD record
ord-9fa6b67941164d9fb3d7bd40aeac2030
Source dataset
uspto-grants-2015_12
Patent number
US09199938B2

Reaction notes

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