Piperidine → HCID 71556357, compound
Reaction equation
C[O:2][C:3]([C:5]1[C:6](Cl)=[N:7][C:8]2[C:13]([C:14]=1[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)=[CH:12][C:11]([Cl:21])=[C:10]([Cl:22])[CH:9]=2)=[O:4].[NH:24]1[CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]1>>[Cl:21][C:11]1[CH:12]=[C:13]2[C:8](=[CH:9][C:10]=1[Cl:22])[N:7]=[C:6]([N:24]1[CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]1)[C:5]([C:3]([OH:2])=[O:4])=[C:14]2[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1Participants
3
Procedure
The title compound was prepared in analogy to example 21 step D from 2,6,7-trichloro-4-phenyl-quinoline-3-carboxylic acid methyl ester and piperidine. Brown solid. MS (ESI): 401.1 (M+H)+.
Sources & evidence
- ORD record
- ord-ab7d047a6d114b9a8f6131565c5e2c4a
- Source dataset
- uspto-grants-2015_12
- Patent number
- US09199938B2
Reaction notes
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