Trifluoroacetic acid → HCID 71556618, compound

HRID 1497124Notes

Reaction equation

HRID 1497124 reaction equation
C([O:5][C:6]([C:8]1[C:9]([N:25]([CH2:27][CH2:28][O:29][CH3:30])[CH3:26])=[N:10][C:11]2[C:16]([C:17]=1[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)=[CH:15][C:14]([Cl:24])=[CH:13][CH:12]=2)=[O:7])(C)(C)C.C(O)(C(F)(F)F)=O>>[Cl:24][C:14]1[CH:15]=[C:16]2[C:11](=[CH:12][CH:13]=1)[N:10]=[C:9]([N:25]([CH2:27][CH2:28][O:29][CH3:30])[CH3:26])[C:8]([C:6]([OH:7])=[O:5])=[C:17]2[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1

Participants

3

Reactant 2

HCID 6422Trifluoroacetic acidHCID 86682971HCID 86682971, compound

Product 1

HCID 71556618HCID 71556618, compound

Procedure

The title compound was prepared in analogy to example 42 step B from 6-chloro-2-[(2-methoxy-ethyl)-methyl-amino]-4-phenyl-quinoline-3-carboxylic acid tert-butyl ester and TFA. Light yellow foam. MS (ESI): 369 (M−H)−.

Sources & evidence

ORD record
ord-33f3e0c2bde44536959bd9720505356c
Source dataset
uspto-grants-2015_12
Patent number
US09199938B2

Reaction notes

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