Piperidine → HCID 71556688, compound

HRID 1497139Notes

Reaction equation

HRID 1497139 reaction equation
C[O:2][C:3]([C:5]1[C:6](Cl)=[N:7][C:8]2[C:13]([C:14]=1[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)=[CH:12][C:11]([C:21]#[N:22])=[CH:10][C:9]=2[CH3:23])=[O:4].[NH:25]1[CH2:30][CH2:29][CH2:28][CH2:27][CH2:26]1>>[C:21]([C:11]1[CH:12]=[C:13]2[C:8](=[C:9]([CH3:23])[CH:10]=1)[N:7]=[C:6]([N:25]1[CH2:30][CH2:29][CH2:28][CH2:27][CH2:26]1)[C:5]([C:3]([OH:2])=[O:4])=[C:14]2[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)#[N:22]

Participants

3

Reactant 2

HCID 8082PiperidineHCID 86682980HCID 86682980, compound

Product 1

HCID 71556688HCID 71556688, compound

Procedure

The title compound was prepared in analogy to example 21 step D from 2-chloro-6-cyano-8-methyl-4-phenyl-quinoline-3-carboxylic acid methyl ester and piperidine. Yellow solid. MS (ESI): 372.2 (M+H)+.

Sources & evidence

ORD record
ord-9118979a148c4ea18b41764a1c5bad49
Source dataset
uspto-grants-2015_12
Patent number
US09199938B2

Reaction notes

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