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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1497166Generated: October 29, 2026

2-Amino-5-chlorobenzophenone → N-(2-Benzoyl-4-chloro-phenyl)-malonamic acid methyl ester

https://huagongshe.com/reaction/1497166

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-5-chlorobenzophenoneHCID 12870—
ReactantMethyl malonyl chlorideHCID 123460—
ProductN-(2-Benzoyl-4-chloro-phenyl)-malonamic acid methyl esterHCID 11624106—

Reaction Steps

The title compound was prepared in analogy to example 21 step A from (2-amino-5-chloro-phenyl)-phenyl-methanone and methyl 3-chloro-3-oxopropanoate. Off-white solid. MS (ESI): 330.1 (M−H)−.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09199938B2
Source datasetuspto-grants-2015_12
ORD IDord-871d20e95b5d450a888493a416e84cfb
Source noteuspto-grants-2015_12