1,1,1-Trifluoro-2-propanol → HCID 86683012, compound

Participants

Reaction Steps

The title compound was prepared in analogy to example 79 step A from 6-chloro-4-(3-isopropyl-phenyl)-2-trifluoromethanesulfonyloxy-quinoline-3-carboxylic acid tert-butyl ester (prepared as described in example 78 step C, 250 mg, 0.47 mmol) and 1,1,1-trifluoro-propan-2-ol (64.57 mg, 0.57 mmol). Off white solid (100 mg, 43%). LC-MS (ESI): 494 (M+H)+.

Provenance & Evidence