HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 71555921, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 86683018 | HCID 86683018 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 71555921 | HCID 71555921 | — |
Reaction Steps
The title compound was prepared in analogy to example 12 step B from a mixture of 6-chloro-4-(2-chloro-benzyl)-2-dimethylamino-8-trifluoromethyl-quinoline-3-carboxylic acid ethyl ester (50 mg, 0.106 mmol) and 1N NaOH in ethanol. Pale yellow solid (22 mg, 47%). LC-MS (ESI): 441 (M−H)−.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09199938B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-067012e52fad416c9aebccc2d7807d68 |
| Source note | uspto-grants-2015_12 |