Isopropanol → HCID 86683028, compound

HRID 1497205Notes

Reaction equation

[CH2:1]([O:3][C:4]([C:6]1[C:7]([O:25]S(C(F)(F)F)(=O)=O)=[N:8][C:9]2[C:14]([C:15]=1[CH2:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=1[Cl:23])=[CH:13][C:12]([Cl:24])=[CH:11][CH:10]=2)=[O:5])[CH3:2].[CH3:33][CH:34](O)[CH3:35]>>[CH2:1]([O:3][C:4]([C:6]1[C:7]([O:25][CH:34]([CH3:35])[CH3:33])=[N:8][C:9]2[C:14]([C:15]=1[CH2:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=1[Cl:23])=[CH:13][C:12]([Cl:24])=[CH:11][CH:10]=2)=[O:5])[CH3:2]

Participants

Reactant 2

HCID 3776Isopropanol

HCID 86682952HCID 86682952, compound

Product 1

HCID 86683028HCID 86683028, compound

Procedure

This compound was prepared in analogy to example 29 step D from 6-chloro-4-(2-chloro-benzyl)-2-trifluoromethanesulfonyloxy-quinoline-3-carboxylic acid ethyl ester (prepared as described in example 29 step C) and propan-2-ol. Off white solid. LC-MS (ESI): 418 (M+H)+.

Sources & evidence

ORD record: ord-1154f18c90854b22954fe0b4ee5056a8
Source dataset: uspto-grants-2015_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09199938B2

Reaction notes

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