1,1,1-Trifluoro-2-propanol → HCID 86683041, compound

Participants

Reaction Steps

The title compound was prepared in analogy to example 92 step A from 6-chloro-4-(3-chloro-phenyl)-2-trifluoromethanesulfonyloxy-quinoline-3-carboxylic acid tert-butyl ester (prepared as described in example 91 step C, 150 mg, 0.29 mmol) and 1,1,1-trifluoro-propan-2-ol (0.052 ml, 0.58 mmol). Sticky pale yellow liquid (70 mg, 50%). LC-MS (ESI): 486 (M+H)+.

Provenance & Evidence