HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2-Amino-5-chlorophenyl)(3-chlorophenyl)methanone → 6-Chloro-4-(3-chloro-phenyl)-2-cyclobutyl-quinoline-3-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2-Amino-5-chlorophenyl)(3-chlorophenyl)methanone | HCID 5231029 | — |
| Reactant | 3-Cyclobutyl-3-oxopropanenitrile | HCID 13861115 | — |
| Product | 6-Chloro-4-(3-chloro-phenyl)-2-cyclobutyl-quinoline-3-carbonitrile | HCID 86683068 | — |
Reaction Steps
The title compound was prepared in analogy to example 101 step B from (2-amino-5-chloro-phenyl)-(3-chloro-phenyl)-methanone (prepared as described in example 91 step A) and 3-cyclobutyl-3-oxo-propionitrile (prepared as described in example 104 step A). Yellow foam. MS (ESI): 353.3 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09199938B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-448ba215560c4c1cbba3a977b60dc6b0 |
| Source note | uspto-grants-2015_12 |