HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2-Amino-5-(trifluoromethyl)phenyl)(phenyl)methanone → 2-(1-Ethyl-propyl)-4-phenyl-6-trifluoromethyl-quinoline-3-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2-Amino-5-(trifluoromethyl)phenyl)(phenyl)methanone | HCID 13014169 | — |
| Reactant | 4-Ethyl-3-oxohexanenitrile | HCID 23505748 | — |
| Product | 2-(1-Ethyl-propyl)-4-phenyl-6-trifluoromethyl-quinoline-3-carbonitrile | HCID 86683069 | — |
Reaction Steps
The title compound was prepared in analogy to example 101 step B from (2-amino-5-trifluoromethyl-phenyl)-phenyl-methanone and 4-ethyl-3-oxo-hexanenitrile (prepared as described in example 101 step A). Off-white solid. MS (ESI): 369.4 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09199938B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-2174e0bae04a4fc7b2dfcda6ebaa7706 |
| Source note | uspto-grants-2015_12 |