Piperidine → HCID 86683081, compound

HRID 1497266Notes

Reaction equation

HRID 1497266 reaction equation
Cl[C:2]1[C:11]([C:12]#[N:13])=[C:10]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:9]2[C:4](=[CH:5][C:6]([O:20][CH3:21])=[CH:7][CH:8]=2)[N:3]=1.[NH:22]1[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]1>>[CH3:21][O:20][C:6]1[CH:5]=[C:4]2[C:9]([C:10]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)=[C:11]([C:12]#[N:13])[C:2]([N:22]3[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]3)=[N:3]2)=[CH:8][CH:7]=1

Participants

3

Reactant 2

HCID 8082PiperidineHCID 86683082HCID 86683082, compound

Product 1

HCID 86683081HCID 86683081, compound

Procedure

The title compound was prepared in analogy to example 27 step C from 2-chloro-7-methoxy-4-phenyl-quinoline-3-carbonitrile and piperidine. Light yellow solid. MS (ESI): 344.5 (M+H)+.

Sources & evidence

ORD record
ord-509f75f0390c46849859ce2745182e0e
Source dataset
uspto-grants-2015_12
Patent number
US09199938B2

Reaction notes

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