Water → HCID 123869272, compound

Participants

Reaction Steps

A solution of (2-Amino-5-bromo-phenyl)-phenyl-methanone (67 g, 244 mmol), 2-Methyl-propane-2-sulfinic acid amide (35.38 g, 292 mmol) and Ti(OEt)4 (111.15 g, 487 mmol) in THF (800 mL) is heated to reflux overnight. Then H2O is added and filtered and concentrated. The residue is purified by chromatography on silica gel to give desired product.

Provenance & Evidence