HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Bromo-7-methyl-8-(3-trifluoromethyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine → 6-Bromo-2-chloro-7-methyl-8-(3-trifluoromethyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Bromo-7-methyl-8-(3-trifluoromethyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine | HCID 86708087 | — |
| Reactant | 5-Bromo-2-chloro-4-methyl-3-(3-trifluoromethyl-phenyl)-pyridine | HCID 86708100 | — |
| Product | 6-Bromo-2-chloro-7-methyl-8-(3-trifluoromethyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridine | HCID 86708115 | — |
Reaction Steps
The title compound was prepared from 6-bromo-7-methyl-8-(3-trifluoromethyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine (Int. 2, 356 mg, 0.959 mmol) using a similar method to that employed in Intermediate 14 (130 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09199984B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-3c4588faab254683b3891d05d046baad |
| Source note | uspto-grants-2015_12 |