Dichloromethane → 6-Chloro-3-(2-fluoro-4-iodo-phenylamino)-pyridazine-4-carboxylic acid (2,2-dimethyl-[1,3]dioxolan-4-ylmethoxy)-amide

HRID 149785Notes

Reaction equation

HRID 149785 reaction equation
[CH3:20][C:21]1([CH3:29])[O:22][CH2:23][CH:24]([CH2:26][O:27][NH2:28])[O:25]1.[CH:30]([N:31]([CH:32]([CH3:33])[CH3:34])[CH2:35][CH3:36])([CH3:37])[CH3:38].[Cl:1][c:2]1[cH:3][c:4]([C:17](=[O:18])[OH:19])[c:5]([NH:8][c:9]2[c:10]([F:16])[cH:11][c:12]([I:15])[cH:13][cH:14]2)[n:6][n:7]1.[Cl:39][CH2:40][Cl:41]>>[Cl:1][c:2]1[cH:3][c:4]([C:17](=[O:19])[NH:28][O:27][CH2:26][CH:24]2[CH2:23][O:22][C:21]([CH3:20])([CH3:29])[O:25]2)[c:5]([NH:8][c:9]2[c:10]([F:16])[cH:11][c:12]([I:15])[cH:13][cH:14]2)[n:6][n:7]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 81531DiisopropylethylamineHCID 10240948O-[(2,2-dimethyl-1,3-dioxolan-4-yl)methyl]hydroxylamineHCID 248220276-Chloro-3-[(2-fluoro-4-iodophenyl)amino]pyridazine-4-carboxylic acid

Product 1

HCID 248220306-Chloro-3-(2-fluoro-4-iodo-phenylamino)-pyridazine-4-carboxylic acid (2,2-dimethyl-[1,3]dioxolan-4-ylmethoxy)-amide

Sources & evidence

ORD record
ord-48ab491142e84646950a64232114946f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…