Hydrochloric Acid → HCID 68641848, compound

Participants

Reaction Steps

Ethanol (1 ml) and a 20% sodium hydroxide aqueous solution were mixed with methyl 5-(4-chloro-2-methoxyphenyl)-2H-pyrazole-3-carboxylate (100 mg) obtained in the Step 18-1-2, and the mixture was heated under reflux. After one hour, the mixture was allowed to cool to a room temperature and acidified with 2-N hydrochloric acid. The precipitated crystal was separated by filtration to give the title compound (90 mg, 95%).

Provenance & Evidence