HCID 117942132, compound → HCID 117951855, compound

Participants

Reaction Steps

The title compound was prepared as described for (S)-8-(2-amino-6-((R)-1-(2′-(ethoxycarbonyl)-4-(3-methyl-1H-pyrazol-1-yl)-[1,1′-biphenyl]-3-yl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)-2,8-diazaspiro[4.5]decane-3-carboxylic acid (Example 20) starting with (S)-8-(2-amino-6-((R)-1-(2-bromo-4-chlorophenyl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)-2-((benzyloxy)carbonyl)-2,8-diazaspiro[4.5]decane-3-carboxylic acid.

Provenance & Evidence