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HRID1499300

反应详情

EQUATION

反应方程式

HRID 1499300 的结构方程式

REACTANTS

反应物

3
结构：O=CO
HCID284

Formic acid

CH2O2

结构：NC(=O)C1(N)CCCC1
HCID11116086

1-AMINO-1-CYCLOPENTANECARBOXAMIDE

C6H12N2O

结构：CS[C@H]1O[C@@H](c2ccc(C)c(Cc3ccc(CCCCNC(C)(C)CO)cc3)c2)[C@H](O)[C@@H](O)[C@@H]1O
HCID90177781

未命名化合物

PRODUCTS

生成物

1
结构：CS[C@H]1O[C@@H](c2ccc(C)c(Cc3ccc(CCCCNC4(C(N)=O)CCCC4)cc3)c2)[C@H](O)[C@@H](O)[C@@H]1O
HCID90183234

未命名化合物

PROCEDURE

实验过程

The same procedure was employed as for amine 24, using 1-aminocyclopentanecarboxamide, to provide the product 26 with 0.5 equivalents of formic acid. 1H NMR (400 MHz, MeOH-d4) δ ppm 8.52 (s, 0.5 H, formate), 6.98-7.22 (m, 7 H), 4.39 (d, J=9.6 Hz, 1 H), 4.13 (d, J=9.3 Hz, 1 H), 3.91-4.01 (m, 2 H), 3.34-3.51 (m, 3 H), 2.50-2.68 (m, 4 H), 2.21 (s, 3 H), 2.14 (s, 3 H), 2.10 (d, J=7.3 Hz, 2 H), 1.73-1.87 (m, 6 H), 1.63-1.72 (m, 2 H), 1.58 (d, J=7.1 Hz, 2 H). MS (ES+) [M+H]+=543.