HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Formic Acid → HCID 90183234, Verbindung
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Formic Acid | HCID 284 | — |
| Edukt | 1-Aminocyclopentanecarboxamide | HCID 11116086 | — |
| Edukt | (2S,3R,4R,5S,6R)-2-(3-(4-(4-((1-hydroxy-2-methylpropan-2-yl)amino)butyl)benzyl)-4-methylphenyl)-6-(methylthio)tetrahydro-2H-pyran-3,4,5-triol | HCID 90177781 | — |
| Produkt | HCID 90183234 | HCID 90183234 | — |
Reaktionsschritte
The same procedure was employed as for amine 24, using 1-aminocyclopentanecarboxamide, to provide the product 26 with 0.5 equivalents of formic acid. 1H NMR (400 MHz, MeOH-d4) δ ppm 8.52 (s, 0.5 H, formate), 6.98-7.22 (m, 7 H), 4.39 (d, J=9.6 Hz, 1 H), 4.13 (d, J=9.3 Hz, 1 H), 3.91-4.01 (m, 2 H), 3.34-3.51 (m, 3 H), 2.50-2.68 (m, 4 H), 2.21 (s, 3 H), 2.14 (s, 3 H), 2.10 (d, J=7.3 Hz, 2 H), 1.73-1.87 (m, 6 H), 1.63-1.72 (m, 2 H), 1.58 (d, J=7.1 Hz, 2 H). MS (ES+) [M+H]+=543.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09200025B2 |
| Quelldatensatz | uspto-grants-2015_12 |
| ORD ID | ord-275dd508c3e14b8d9e55bae9eb265211 |
| Quellennotiz | uspto-grants-2015_12 |