Cyanuric chloride → HCID 86677726, compound

HRID 1499803Notes

Reaction equation

HRID 1499803 reaction equation
[Cl:1][C:2]1[C:3]([F:25])=[C:4]([CH:14]2[CH2:17][N:16]([C:18]([O:20][C:21]([CH3:24])([CH3:23])[CH3:22])=[O:19])[CH2:15]2)[C:5]([O:11][CH2:12][CH3:13])=[C:6]([CH:8](O)[CH3:9])[CH:7]=1.N1C(Cl)=NC(Cl)=NC=1[Cl:28]>>[Cl:1][C:2]1[C:3]([F:25])=[C:4]([CH:14]2[CH2:17][N:16]([C:18]([O:20][C:21]([CH3:24])([CH3:23])[CH3:22])=[O:19])[CH2:15]2)[C:5]([O:11][CH2:12][CH3:13])=[C:6]([CH:8]([Cl:28])[CH3:9])[CH:7]=1

Participants

3

Reactant 2

HCID 7954Cyanuric chlorideHCID 86677727Tert-butyl 3-[3-chloro-6-ethoxy-2-fluoro-5-(1-hydroxyethyl)phenyl]azetidine-1-carboxylate

Product 1

HCID 86677726HCID 86677726, compound

Procedure

This compound was prepared according to the procedure of Example 13 step 6, using tert-butyl 3-[3-chloro-6-ethoxy-2-fluoro-5-(1-hydroxyethyl)phenyl]azetidine-1-carboxylate (racemic) and cyanuric chloride as the starting materials.

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-e9253a533b6040e88cb80e65e04b8654
Source dataset
uspto-grants-2015_12
Patent number
US09199982B2

Reaction notes

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