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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1499809Generated: October 30, 2026

HCID 86677726, compound → tert-Butyl 3-{3-[1-(4-amino-3-iodo-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl]-5-chloro-2-ethoxy-6-fluorophenyl}azetidine-1-carboxylate

https://huagongshe.com/reaction/1499809

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86677726HCID 86677726—
ReactantHCID 178508725HCID 178508725—
Producttert-Butyl 3-{3-[1-(4-amino-3-iodo-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl]-5-chloro-2-ethoxy-6-fluorophenyl}azetidine-1-carboxylateHCID 86677733—

Reaction Steps

This compound was prepared using procedures analogous to those for Example 139 step 5, with racemic tert-butyl 3-[3-chloro-5-(1-chloroethyl)-6-ethoxy-2-fluorophenyl]azetidine-1-carboxylate from Example 139 Step 4 and 3-iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine as starting materials. LCMS calculated for C23H28ClFIN6O3 (M+H)+: m/z=617.1; Found:617.1

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09199982B2
Source datasetuspto-grants-2015_12
ORD IDord-3af3df5e1bdc46289f1bbca76fbae204
Source noteuspto-grants-2015_12