HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Bromo-4-iodobenzene → 4'-bromo-[1,1'-Biphenyl]-4-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Bromo-4-iodobenzene | HCID 11522 | — |
| Reactant | 4-Cyanophenylboronic acid | HCID 2734326 | — |
| Solvent | 2,4-Dichloro-6-phenylpyrimidine | HCID 241554 | — |
| Product | 4'-bromo-[1,1'-Biphenyl]-4-carbonitrile | HCID 1394462 | — |
Reaction Steps
4-bromo-4′-cyanobiphenyl was synthesized by the same method as in syntheses of 2,4-dichloro-6-phenylpyrimidine in the above (3-1-1), except that 4-bromoiodobenzene was used in place of 2,4,6-trichloropyrimidine and that 4-cyanophenylboronic acid was used in place of phenylboronic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09203043B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-58606253032a44db9bf11a4308ca0e1d |
| Source note | uspto-grants-2015_12 |