Hydrochloric Acid → 1909318-80-4

HRID 1500069Notes

Reaction equation

HRID 1500069 reaction equation
[O:1]=[S:2]1(=[O:8])[CH2:5][CH:4]([C:6]#[N:7])[CH2:3]1.[ClH:9]>CO.[Ni]>[ClH:9].[O:1]=[S:2]1(=[O:8])[CH2:5][CH:4]([CH2:6][NH2:7])[CH2:3]1

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 296719500881-65-2

Product 1

HCID 867306911909318-80-4

Reagents, catalysts & solvents 2

HCID 935NickelCatalystHCID 887MethanolSolvent

Procedure

1,1-dioxothietane-3-carbonitrile (0.1 g) dissolved in methanol (45 ml) was passed through H-Cube equipped with a Ra—Ni cartridge at 50 bars, 1 ml/min and room temperature. The reaction mixture was poured into HCl (4M in dioxane) and after evaporation of the solvent, 60 mg of (1,1-dioxothietan-3-yl)methanamine hydrochloride as a yellow solid was obtained. 1H NMR (D2O): 4.49-4.49 (m, 2H); 4.2-4.07 (m, 2H); 3.46 (d, 1H, J=7.3 Hz); 3.34 (d, 1H, J=7.3 Hz); 3.12-2.93 (m, 1H).

Workup

  1. customafter evaporation of the solvent

Sources & evidence

ORD record
ord-ad38206f74d14b37a01cd1034a888694
Source dataset
uspto-grants-2015_12
Patent number
US09204648B2

Reaction notes

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