Isopropanol → HCID 58500191, compound

HRID 1500166Notes

Reaction equation

HRID 1500166 reaction equation
[N+:1](/[CH:4]=C/C1OC=CC=1)([O-:3])=[O:2].[CH:11](=[O:15])[CH:12]([CH3:14])[CH3:13].C[CH:17]([OH:19])C.CCC[CH2:23][CH2:24][CH3:25].[CH:26](Cl)(Cl)Cl>>[O:15]1[CH:26]=[CH:13][C:12]([C@H:14]([CH2:4][N+:1]([O-:3])=[O:2])[C:24]([CH3:23])([CH3:25])[CH:17]=[O:19])=[CH:11]1

Participants

6

Reactant 5

HCID 3776IsopropanolHCID 6212ChloroformHCID 6561IsobutyraldehydeHCID 8058HexaneHCID 6873312-(B-NITROVINYL)FURAN

Product 1

HCID 58500191HCID 58500191, compound

Procedure

The title compound was prepared from trans-2-(2-nitrovinyl) furan, and isobutyraldehyde according to general procedure. The enantiomeric excess was determined by HPLC with Chiralpak OD-H column at 210 nm (2-propanol:hexane=20:80), 1 mL/min, tmajor=12.5 min, tminor=8.3 min, [α]D20=+1.5 (c=2.8, CHCl3);

Sources & evidence

ORD record
ord-3beb91e64953436fb4505bbbfca00f75
Source dataset
uspto-grants-2015_12
Patent number
US09206090B2

Reaction notes

Loading…