HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropanol → HCID 58500188, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropanol | HCID 3776 | — |
| Reactant | Hexane | HCID 8058 | — |
| Reactant | 3-Methylbutanal | HCID 11552 | — |
| Reactant | trans-4-Bromo-beta-nitrostyrene | HCID 688204 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 58500188 | HCID 58500188 | — |
Reaction Steps
The title compound was prepared from (E)-1-bromo-4-(2-nitrovinyl)benzene and isovaleraldehyde according to general procedure. The enantiomeric excess was determined by HPLC with Chiralpak AD-H column at 254 nm (2-propanol:hexane=10:90), 1 mL/min, tmajor=7.6 min, tminor=7.2 min, the diastereomeric ratio was determined by 1H NMR. [α]D20=−30.2 (c=0.27, CHCl3);
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09206090B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-d6c768030f85418fb76dd23fdd21848c |
| Source note | uspto-grants-2015_12 |