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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1500291Generated: November 1, 2026

Ethyl difluoroacetate → HCID 86713177, compound

https://huagongshe.com/reaction/1500291

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl difluoroacetateHCID 9961—
Reactant(2S,1R)-2-Amino-3-fluoro-1-(4-iodo-phenyl)-propan-1-olHCID 45257860—
ProductHCID 86713177HCID 86713177—

Reaction Steps

Using the same procedure as Step 1 of Example 4 and reacting ethyldifluoroacetate with commercially available (1R,2S)-2-amino-3-fluoro-1-(4-iodophenyl)propan-1-ol the title compound is obtained (18.3 g): m/z 373 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09206126B2
Source datasetuspto-grants-2015_12
ORD IDord-583b234c033746b18a36a322d127868f
Source noteuspto-grants-2015_12