Hydrochloric Acid → 4-Chlorobenzo(b)thiophene-2-carboxylic Acid

Participants

Reaction Steps

Sodium 4-chlorobenzo[b]thiophen-2-carboxylate (2.40 g) was dissolved in water (33 ml) at 60° C. Concentrated hydrochloric acid (1.3 ml) was added to the solution at the same temperature, and the resulting mixture was stirred. The precipitated crystals were collected by filtration, washed with water, and then dried to obtain 2-carboxy-4-chlorobenzo[b]thiophene.

Provenance & Evidence