Diisopropylethylamine → HCID 67370966, compound

Participants

Reaction Steps

Diisopropylethylamine (2.30 mL, 13.20 mmol) and tetrahydro-2H-pyran-4-amine acetate (526 mg, 3.28 mmol) were added to a stirred suspension of 3-(4-chloro-5-nitropyrimidin-2-yl)pyrazolo[1,5-a]pyrazine (Preparation 24e, 0.91 g, 3.29 mmol) in tetrahydrofuran (15 mL) and the mixture was stirred at room temperature for 3 hours. The solvent was evaporated and water was added. The mixture was filtered to give the title compound (0.785 g, 70%) as a yellow solid.

Provenance & Evidence