HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(6-Chloropyrazin-2-yl)pyrazolo[1,5-a]pyridine → 3-(6-Chloropyrazin-2-yl)pyrazolo[1,5-a]pyrazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(6-Chloropyrazin-2-yl)pyrazolo[1,5-a]pyridine | HCID 58303483 | — |
| Reactant | 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-YL)pyrazolo(1, 5-A)pyrazine | HCID 67372227 | — |
| Product | 3-(6-Chloropyrazin-2-yl)pyrazolo[1,5-a]pyrazine | HCID 86691783 | 28% |
Reaction Steps
Obtained as a yellow solid (28% yield, two steps) from 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazolo[1,5-a]pyrazine (Preparation 29a) according to the experimental procedure as described in Preparation 27b followed by purification by flash chromatography (2:8 ethyl acetate/hexane).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09206183B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-203d7731093c42ae86e077e2fe7f80f1 |
| Source note | uspto-grants-2015_12 |