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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 150090Generated: October 31, 2026

Dichloromethane → 5-chloro-N-[1-(cyanomethyl)-2-oxo-1,2,3,4-tetrahydroquinolin-3-yl]-1H-indole-2-carboxamide

https://huagongshe.com/reaction/150090

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantEthyl AcetateHCID 8857—
Reactant1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 15908—
Reactant1-HydroxybenzotriazoleHCID 75771—
ReactantDiisopropylethylamineHCID 81531—
Reactant5-Chloro-1H-indole-2-carboxylic acidHCID 82693—
Reactant(3-amino-2-oxo-3,4-dihydroquinolin-1(2H)-yl)acetonitrileHCID 21906832—
Product5-chloro-N-[1-(cyanomethyl)-2-oxo-1,2,3,4-tetrahydroquinolin-3-yl]-1H-indole-2-carboxamideHCID 10045242—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-91af271045c64ab5b81b212cff3ec1f2
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)