Dichloromethane → 5-chloro-N-[1-(cyanomethyl)-2-oxo-1,2,3,4-tetrahydroquinolin-3-yl]-1H-indole-2-carboxamide
Reaction equation
[CH3:33][CH2:34][N:35]=[C:36]=[N:37][CH2:38][CH2:39][CH2:40][N:41]([CH3:42])[CH3:43].[CH3:62][CH2:63][O:64][C:65]([CH3:66])=[O:67].[CH:24]([N:25]([CH2:26][CH3:27])[CH:28]([CH3:29])[CH3:30])([CH3:31])[CH3:32].[Cl:11][c:12]1[cH:13][c:14]2[cH:15][c:16]([C:21](=[O:22])[OH:23])[nH:17][c:18]2[cH:19][cH:20]1.[Cl:59][CH2:60][Cl:61].[NH2:44][CH:45]1[C:46](=[O:58])[N:47]([CH2:55][C:56]#[N:57])[c:48]2[cH:49][cH:50][cH:51][cH:52][c:53]2[CH2:54]1.[OH:1][n:2]1[c:3]2[c:4]([cH:5][cH:6][cH:7][cH:8]2)[n:9][n:10]1>>[Cl:11][c:12]1[cH:13][c:14]2[cH:15][c:16]([C:21](=[O:23])[NH:44][CH:45]3[C:46](=[O:58])[N:47]([CH2:55][C:56]#[N:57])[c:48]4[cH:49][cH:50][cH:51][cH:52][c:53]4[CH2:54]3)[nH:17][c:18]2[cH:19][cH:20]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-91af271045c64ab5b81b212cff3ec1f2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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