Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | HCID 178479280 | HCID 178479280 | — |
| Product | HCID 178472515 | HCID 178472515 | — |
Reaction Steps
To a solution of trans-3-aminocyclobutanecarboxylic acid hydrochloride (1.0 g, 6.5 mmol) in 20 mL of EtOH was added 10 mL of SOCl2 dropwise at 0° C. The resulting mixture was heated with stirring at 100° C. for 16 hours. And then, the solvent was evaporated to afford the residue which was used in the next step directly.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09206191B2 |
|---|
| Source dataset | uspto-grants-2015_12 |
|---|
| ORD ID | ord-e880b4739f6b4eb7b78e4ec8902e36a8 |
|---|
| Source note | uspto-grants-2015_12 |
|---|
