HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-[(2-Amino-4-chlorophenyl)amino]-1,1,1-trifluoro-2-methylbutan-2-ol → 4-(5-chloro-2-{[3-(methylsulfonyl)-1H-pyrazolo[3,4-c]pyridin-1-yl]methyl}-1H-benzimidazol-1-yl)-1,1,1-trifluoro-2-methylbutan-2-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-[(2-Amino-4-chlorophenyl)amino]-1,1,1-trifluoro-2-methylbutan-2-ol | HCID 89923892 | — |
| Reactant | 3-methanesulfonyl-1H-indazole | HCID 178504856 | — |
| Reactant | HCID 178504858 | HCID 178504858 | — |
| Product | 4-(5-chloro-2-{[3-(methylsulfonyl)-1H-pyrazolo[3,4-c]pyridin-1-yl]methyl}-1H-benzimidazol-1-yl)-1,1,1-trifluoro-2-methylbutan-2-ol | HCID 72948900 | — |
Reaction Steps
The title compound was prepared in analogy to Example 2-1 by using 4-[(2-amino-4-chlorophenyl)amino]-1,1,1-trifluoro-2-methylbutan-2-ol and 3-(methylsulfonyl)-1H-pyrazolo[3,4-c]pyridine instead of 4-chloro-N—((R)-1,1-dioxo-tetrahydro-1λ6-thiophen-3-yl)-benzene-1,2-diamine and 3-methanesulfonyl-1H-indazole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09206191B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-8c54fd4fd9d4423098f48e67bdadcadf |
| Source note | uspto-grants-2015_12 |