Phenethyl bromide → HCID 131734281, compound

HRID 1501279Notes

Reaction equation

HRID 1501279 reaction equation
[Br:1][CH2:2][CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[CH3:10][C:11]1[CH:21]=[N:20][CH:19]=[C:18]([CH3:22])[C:12]=1[C:13]([O:15][CH2:16][CH3:17])=[O:14]>O1CCOCC1>[Br-:1].[CH2:16]([O:15][C:13]([C:12]1[C:11]([CH3:10])=[CH:21][N+:20]([CH:3]([C:4]2[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=2)[CH3:2])=[CH:19][C:18]=1[CH3:22])=[O:14])[CH3:17]

Participants

4

Reactant 2

HCID 7666Phenethyl bromideHCID 59589494Ethyl 3,5-dimethylisonicotinate

Product 1

HCID 131734281HCID 131734281, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

1-(bromoethyl)benzene (1.3 g, 7.03 mmol) was added to ethyl 3,5-dimethylisonicotinate (0.7 g, 3.91 mmol) in dioxane (20 mL) and the resultant mixture was stirred at reflux overnight. The resulting solution was used to the next step without further purification.

Workup

  1. temperatureat reflux overnight
  2. customThe resulting solution was used to the next step without further purification

Sources & evidence

ORD record
ord-1545a96e18274b38a21c98eaddbfa007
Source dataset
uspto-grants-2015_12
Patent number
US09206128B2

Reaction notes

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