HCID 117690302, compound → HCID 89633494, compound

Participants

Reaction Steps

To the solution of (3R,9aS)-8-benzyl 2-tert-butyl 3-((R)-3-methyl-1-oxoisochroman-6-yl)tetrahydro-1H-pyrazino[1,2-a]pyrazine-2,8(9H,9aH)-dicarboxylate (0.590 g, 1.10 mmol) in methanol (20 mL) was added palladium on carbon (10%, 0.117 g, 0.110 mmol) and the mixture was subjected to hydrogenation at rt overnight. After filtration the filtrate was concentrated to give the title compound.

Provenance & Evidence