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HRID1502080

反应详情

EQUATION

反应方程式

HRID 1502080 的结构方程式

REACTANTS

反应物

2
结构：Cc1c([C@@H]2CN3CCNC[C@@H]3CO2)ccc(F)c1C#N
HCID71273584

未命名化合物

结构：Cc1cc([C@@H]2CN3CCN(C(=O)OC(C)(C)C)C[C@H]3CO2)c(C)c(C#N)c1F
HCID89633504

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cc([C@@H]2CN3CCN(C(=O)OC(C)(C)C)C[C@@H]3CO2)c(C)c(C#N)c1F
HCID89633507

未命名化合物

PROCEDURE

实验过程

(3R,9aR)-tert-Butyl 3-(3-cyano-4-fluoro-2,5-dimethylphenyl)hexahydropyrazino[2,1-c][1,4]oxazine-8(1H)-carboxylate was prepared in an analogous fashion to that described for the synthesis of (3R,9aS)-tert-butyl 3-(3-cyano-4-fluoro-2,5-dimethylphenyl)hexahydropyrazino[2,1-c][1,4]oxazine-8(1H)-carboxylate starting from 6-fluoro-2-methyl-3-((3R,9aR)-octahydropyrazino[2,1-c][1,4]oxazin-3-yl)benzonitrile.