HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-3-methoxy-5-nitropyridine → 2-(3-methoxy-5-(1H-tetrazol-1-yl)pyridin-2-yl)acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-3-methoxy-5-nitropyridine | HCID 23456152 | — |
| Reactant | [6-(1H-Tetrazol-1-yl)pyridine-3-yl]acetic acid | HCID 66524945 | — |
| Reactant | 2-(5-(1H-tetrazol-1-yl)pyridin-2-yl)acetic acid | HCID 67517676 | — |
| Product | 2-(3-methoxy-5-(1H-tetrazol-1-yl)pyridin-2-yl)acetic acid | HCID 89618980 | — |
Reaction Steps
The title compound was prepared in an analagous fashion to that described for the syntheses of [6-(1H-tetrazol-1-yl)pyridin-3-yl]acetic acid (Method 1, Steps B-F and [5-(1H-tetrazol-1-yl)pyridin-2-yl]acetic acid (Steps A-E) starting from 2-chloro-3-methoxy-5-nitropyridine. LC/MS: [(M+1-28)]+=208.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09206199B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-b1c66e2c559f4f32b0b97db5e2db7c91 |
| Source note | uspto-grants-2015_12 |