Potassium Carbonate → HCID 131734305, compound

Participants

Reaction Steps

Potassium carbonate (0.48 g, 3.46 mmol) and tert-butyl {7-[(1-{4-[(5-iodopentyl)oxy]phenyl}-2-methylindolizin-3-yl)carbonyl]-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl}acetate (0.50 g, 0.69 mmol) are added to a solution of 2-(2-aminoethoxy)ethanol (0.73 g, 6.93 mmol) in 7 mL of DMF. The solution is stirred for 24 h at ambient temperature and then run into a molar solution of KHSO4. The precipitate formed is filtered off, washed with water and dried under vacuum to give 380 mg (yield: 79%) of a brown powder.

Provenance & Evidence